论文标题
关于流体流动模拟中流体结构相互作用的影响：狭窄的冠状动脉基准测试
On the Impact of Fluid Structure Interaction in Blood Flow Simulations: Stenotic Coronary Artery Benchmark
论文作者
论文摘要
我们研究了使用流体结构相互作用（FSI）模拟大型动脉中的血流的影响。我们将使用刚性几何设置中的Navier-Stokes与完全耦合的FSI模型进行比较。关于几个临床重要性问题，研究血管弹性的相关性。也就是说，我们研究了使用FSI对壁剪应力分布，分数流量储备以及stenosis对脉动循环中压力振幅的阻尼效应的影响。耦合问题在基于任意拉格朗日欧拉（ALE）坐标的整体变化公式中描述。为了进行比较，我们在预应力的几何形状上执行纯Navier-Stokes模拟，以良好的两种配置匹配。提出和讨论了一系列涵盖重要血液动力学因素的数值模拟。
We study the impact of using fluid-structure interactions (FSI) to simulate blood flow in a large stenosed artery. We compare typical flow configurations using Navier-Stokes in a rigid geometry setting to a fully coupled FSI model. The relevance of vascular elasticity is investigated with respect to several questions of clinical importance. Namely, we study the effect of using FSI on the wall shear stress distribution, on the Fractional Flow Reserve and on the damping effect of a stenosis on the pressure amplitude during the pulsatory cycle. The coupled problem is described in a monolithic variational formulation based on Arbitrary Lagrangian Eulerian (ALE) coordinates. For comparison, we perform pure Navier-Stokes simulations on a prestressed geometry to give a good matching of both configurations. A series of numerical simulations that cover important hemodynamical factors are presented and discussed.
