论文标题
动态压缩传感用于实时层析成像重建
Dynamic Compressed Sensing for Real-Time Tomographic Reconstruction
论文作者
论文摘要
随着压缩感应的最新进展,电子断层扫描的分辨率和质量更高。压缩传感(CS)理论利用固有的稀疏信号结构从纳米级的有效地重建三维(3D)体积,并通过取消采样测量值。但是,该过程的瓶颈3D重建具有从小时到几天运行的计算时间。在这里,我们演示了一个动态压缩传感的框架,该框架会产生3D试样结构,该结构在收集新样品投影时实时更新。研究人员可以开始解释3D样品,因为收集数据以促进高通量和互动分析。使用扫描透射电子显微镜(STEM),我们表明动态压缩传感会加速收敛速度3倍,同时对于AU/SRTIO3纳米粒子样品,其误差也将其误差降低了27%。在完成断层扫描实验之前,3D断层图在完成的33%以内具有可解释的结构,并且最早可在66%的时间内看到细节。实验完成后,产生了高保真3D可视化,而不会进一步延迟。此外,可以在整个计算过程中操纵调整数据保真度的重建参数,而无需重新整个过程。
Electron tomography has achieved higher resolution and quality at reduced doses with recent advances in compressed sensing. Compressed sensing (CS) theory exploits the inherent sparse signal structure to efficiently reconstruct three-dimensional (3D) volumes at the nanoscale from undersampled measurements. However, the process bottlenecks 3D reconstruction with computation times that run from hours to days. Here we demonstrate a framework for dynamic compressed sensing that produces a 3D specimen structure that updates in real-time as new specimen projections are collected. Researchers can begin interpreting 3D specimens as data is collected to facilitate high-throughput and interactive analysis. Using scanning transmission electron microscopy (STEM), we show that dynamic compressed sensing accelerates the convergence speed by 3-fold while also reducing its error by 27% for an Au/SrTiO3 nanoparticle specimen. Before a tomography experiment is completed, the 3D tomogram has interpretable structure within 33% of completion and fine details are visible as early as 66%. Upon completion of an experiment, a high-fidelity 3D visualization is produced without further delay. Additionally, reconstruction parameters that tune data fidelity can be manipulated throughout the computation without rerunning the entire process.