论文标题

Scadnano:一种基于浏览器的可拼写工具,用于设计DNA纳米结构

scadnano: A browser-based, scriptable tool for designing DNA nanostructures

论文作者

Doty, David, Lee, Benjamin L, Stérin, Tristan

论文摘要

我们介绍了$ \ textit {scadnano} $(https://scadnano.org)(用于“ scriptable cadnano”的简短),这是一种用于设计合成DNA结构的计算工具。它的设计主要基于Cadnano,这是设计DNA折纸的最广泛使用的软件,具有三个主要区别: 1。Scadnano完全在浏览器中运行,$ \ textit {no software installation} $所需。 2。scadnano设计虽然可以手动编辑,但也可以由$ \ textit {python python脚本库} $创建和编辑,以帮助自动化繁琐的任务。 3。scadnano文件格式为$ \ textit {易于人读} $。此目标与脚本库紧密匹配,旨在在调试脚本或与其他软件接口时会有所帮助。该格式比Cadnano的格式更具表现力,能够描述更广泛的DNA结构,而不仅仅是DNA折纸。

We introduce $\textit{scadnano}$ (https://scadnano.org) (short for "scriptable cadnano"), a computational tool for designing synthetic DNA structures. Its design is based heavily on cadnano, the most widely-used software for designing DNA origami, with three main differences: 1. scadnano runs entirely in the browser, with $\textit{no software installation}$ required. 2. scadnano designs, while they can be edited manually, can also be created and edited by a $\textit{well-documented Python scripting library}$, to help automate tedious tasks. 3. The scadnano file format is $\textit{easily human-readable}$. This goal is closely aligned with the scripting library, intended to be helpful when debugging scripts or interfacing with other software. The format is also somewhat more expressive than that of cadnano, able to describe a broader range of DNA structures than just DNA origami.

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