论文标题
在19009大流行期间对室内级的非药物干预进行建模:基于行人动力学的微观模拟方法
Modeling indoor-level non-pharmaceutical interventions during the COVID-19 pandemic: a pedestrian dynamics-based microscopic simulation approach
论文作者
论文摘要
流行病扩散的数学模型已被广泛采用,以估计流行病的威胁(即,COVID-19大流行)以及评估流行病控制干预措施。室内场所被认为是一个重要的流行病风险来源,但是由于人们之间的动态物理距离变化被忽略,因此现有的广泛使用的流行病扩散模型通常受到室内场所的限制,而本质和非必要旅行的经验特征也没有区分。在本文中,我们介绍了一种基于行人的流行病模型,该模型能够在人们的社交活动期间对室内传播风险进行建模。利用马里兰州Covid-19 Impact Analysis平台的前后流动数据,发现一旦他们的旅行频率仅限于低水平,人们就会倾向于在杂货店花费更多的时间。换句话说,停留时间的增加可以平衡旅行频率的下降并满足人们的需求。基于基于行人的模型和经验证据,评估了来自不同操作水平的非药物干预措施。数值模拟表明,对人们的旅行频率和开放时间的限制在降低每个访问该地点的行人的平均感染风险方面可能并不普遍有效。入境限制可以是一种有效的替代方案,而决策者需要平衡风险接触的减少以及在可能阻碍人们满足旅行需求的地方以外的队列长度的增加。
Mathematical modeling of epidemic spreading has been widely adopted to estimate the threats of epidemic diseases (i.e., the COVID-19 pandemic) as well as to evaluate epidemic control interventions. The indoor place is considered to be a significant epidemic spreading risk origin, but existing widely-used epidemic spreading models are usually limited for indoor places since the dynamic physical distance changes between people are ignored, and the empirical features of the essential and non-essential travel are not differentiated. In this paper, we introduce a pedestrian-based epidemic spreading model that is capable of modeling indoor transmission risks of diseases during people's social activities. Taking advantage of the before-and-after mobility data from the University of Maryland COVID-19 Impact Analysis Platform, it's found that people tend to spend more time in grocery stores once their travel frequencies are restricted to a low level. In other words, an increase in dwell time could balance the decrease in travel frequencies and satisfy people's demand. Based on the pedestrian-based model and the empirical evidence, combined non-pharmaceutical interventions from different operational levels are evaluated. Numerical simulations show that restrictions on people's travel frequency and open-hours of indoor places may not be universally effective in reducing average infection risks for each pedestrian who visit the place. Entry limitations can be a widely effective alternative, whereas the decision-maker needs to balance the decrease in risky contacts and the increase in queue length outside the place that may impede people from fulfilling their travel needs.