论文标题
基于视觉的MDS-UPDRS步态评分评估帕金森氏病运动严重程度
Vision-based Estimation of MDS-UPDRS Gait Scores for Assessing Parkinson's Disease Motor Severity
论文作者
论文摘要
帕金森氏病(PD)是一种进行性神经系统疾病,主要影响运动功能,导致静止,僵硬,胸肌和姿势不稳定。 PD障碍的身体严重程度可以通过运动障碍协会统一帕金森氏病评级量表(MDS-UPDRS)来量化,这是一种广泛使用的临床评级量表。疾病进展的准确和定量评估对于开发一种减慢或停止进一步发展疾病的治疗至关重要。先前的工作主要集中于多巴胺转运神经影像学,以评估运动障碍的诊断或昂贵且侵入性的可穿戴设备。我们第一次提出了一个基于计算机视觉的模型,该模型观察了个人的非侵入性视频记录,提取其3D身体骨架,对其进行跟踪,并根据MDS-UPDRS步态得分对运动进行分类。实验结果表明,我们提出的方法的性能明显优于机会和竞争方法,F1得分为0.83,平衡精度为81%。这是根据MDS-UPDRS步态严重程度对PD患者进行分类的第一个基准,并且可能是疾病严重程度的客观生物标志物。我们的工作证明了如何使用计算机辅助技术来监测患者及其运动障碍。该代码可在https://github.com/mlu355/pd-motor-severity-esimation上获得。
Parkinson's disease (PD) is a progressive neurological disorder primarily affecting motor function resulting in tremor at rest, rigidity, bradykinesia, and postural instability. The physical severity of PD impairments can be quantified through the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS), a widely used clinical rating scale. Accurate and quantitative assessment of disease progression is critical to developing a treatment that slows or stops further advancement of the disease. Prior work has mainly focused on dopamine transport neuroimaging for diagnosis or costly and intrusive wearables evaluating motor impairments. For the first time, we propose a computer vision-based model that observes non-intrusive video recordings of individuals, extracts their 3D body skeletons, tracks them through time, and classifies the movements according to the MDS-UPDRS gait scores. Experimental results show that our proposed method performs significantly better than chance and competing methods with an F1-score of 0.83 and a balanced accuracy of 81%. This is the first benchmark for classifying PD patients based on MDS-UPDRS gait severity and could be an objective biomarker for disease severity. Our work demonstrates how computer-assisted technologies can be used to non-intrusively monitor patients and their motor impairments. The code is available at https://github.com/mlu355/PD-Motor-Severity-Estimation.