论文标题
两个暴露之间的相互作用:确定风险估计的赔率和置信区间
Interaction between two exposures: determining odds ratios and confidence intervals for risk estimates
论文作者
论文摘要
在流行病学研究中,通常会研究诸如疾病之类的危险因素之间的相互作用,从而估计与正在调查的两个危险因素中的两种或两个暴露有关的风险。可以使用相同的回归模型在添加性和乘法刻度上估算相互作用。我们在这里提出了一项评论,用于计算相互作用,并使用单个回归模型以及措施之间的关系,尤其是合并的暴露风险组的标准误差,估算两个暴露的风险和置信区间。
In epidemiological research, it is common to investigate the interaction between risk factors for an outcome such as a disease and hence to estimate the risk associated with being exposed for either or both of two risk factors under investigation. Interactions can be estimated both on the additive and multiplicative scale using the same regression model. We here present a review for calculating interaction and estimating the risk and confidence interval of two exposures using a single regression model and the relationship between measures, particularly the standard error for the combined exposure risk group.