论文标题
泄漏整合神经元网络中的凸起吸引子和波浪
Bump attractors and waves in networks of leaky integrate-and-fire neurons
论文作者
论文摘要
在空间扩展的神经生物学网络的体内实验中观察到的凸起吸引子正在徘徊在局部模式中。它们对于大脑的导航系统和特定的内存任务很重要。撞击器的特征是神经元经常发射的核心,而远离核心的核心则不会开火。我们在古典网络中揭示了碰撞吸引子与流行浪之间的关系,该网络具有令人兴奋的,漏水和开火的神经元的关系。这种关系与在管道湍流开始时的复杂时空图案和波浪之间具有很强的相似性。尖峰网络中的波是由射击集确定的,即神经元在波传播时达到阈值和射击的时间的集合。我们定义和研究电压映射的分析特性,该电压映射是一个将溶液的放电设置转换为其时空曲线的操作员。该操作员允许我们在核心上构建具有任意数量的尖峰的局部行进波,并研究其线性稳定性。网络中存在均匀的“层流”状态,并且对于主控制参数的所有值,它是线性稳定的。对同质状态的足够广泛的干扰引起了碰撞吸引子。我们表明,一个人可以用核心的尖峰数量构建波浪。尖峰的数量越高,波浪的速度越慢,并且其轮廓越类似于固定的凸起。就像在流体动力的类比中一样,这种波与同质状态共存的波动是不稳定的,并且它们所属的溶液分支与层状状态断开;我们提供的证据表明,凸起吸引子的动力学显示了不稳定波的回声,这些波浪形成了其构成块。
Bump attractors are wandering localised patterns observed in in vivo experiments of spatially-extended neurobiological networks. They are important for the brain's navigational system and specific memory tasks. A bump attractor is characterised by a core in which neurons fire frequently, while those away from the core do not fire. We uncover a relationship between bump attractors and travelling waves in a classical network of excitable, leaky integrate-and-fire neurons. This relationship bears strong similarities to the one between complex spatiotemporal patterns and waves at the onset of pipe turbulence. Waves in the spiking network are determined by a firing set, that is, the collection of times at which neurons reach a threshold and fire as the wave propagates. We define and study analytical properties of the voltage mapping, an operator transforming a solution's firing set into its spatiotemporal profile. This operator allows us to construct localised travelling waves with an arbitrary number of spikes at the core, and to study their linear stability. A homogeneous "laminar" state exists in the network, and it is linearly stable for all values of the principal control parameter. Sufficiently wide disturbances to the homogeneous state elicit the bump attractor. We show that one can construct waves with a seemingly arbitrary number of spikes at the core; the higher the number of spikes, the slower the wave, and the more its profile resembles a stationary bump. As in the fluid-dynamical analogy, such waves coexist with the homogeneous state, are unstable, and the solution branches to which they belong are disconnected from the laminar state; we provide evidence that the dynamics of the bump attractor displays echoes of the unstable waves, which form its building blocks.