论文标题
超分辨率光波动显微镜的最佳相关顺序
Optimal correlation order in super-resolution optical fluctuation microscopy
论文作者
论文摘要
在这里,我们表明,与普遍的意见相反,超分辨率光波动显微镜可能不会导致理想的无限超分辨率增强,随着测得的累积液的增加。使用信息分析来估计确定点源位置的误差界限,我们表明,每次测量的可达到的精度可能会随着超分辨率制度中测得的累积液的增加而饱和。实际上,还有一个最佳的相关顺序,除了三个和更多点源的对象,几乎没有改进。但是,对于仅两个来源的对象,一个仍然具有直观的预期分辨率随累积顺序增加。
Here, we show that, contrary to the common opinion, the super-resolution optical fluctuation microscopy might not lead to ideally infinite super-resolution enhancement with increasing of the order of measured cumulants. Using information analysis for estimating error bounds on the determination of point sources positions, we show that reachable precision per measurement might be saturated with increasing of the order of the measured cumulants in the super-resolution regime. In fact, there is an optimal correlation order beyond which there is practically no improvement for objects of three and more point sources. However, for objects of just two sources, one still has an intuitively expected resolution increase with the cumulant order.