论文标题
对疫苗接种和血浆输血的最佳控制，对Covid-19的潜在有用性
Optimal control of vaccination and plasma transfusion with potential usefulness for COVID-19
论文作者
论文摘要
SEIR模型是一种用于模拟流行动力学的隔室模型。在本章中，我们在代表疫苗接种和血浆输血的隔室SEIR模型中介绍了两个控制功能。提出了最佳控制问题，以研究这两种控制措施的影响，对感染者的减少和恢复措施的增加，成本最低。据我们所知，血浆输血治疗从未被视为缓解流行病的控制策略。拟议的疫苗接种和治疗策略可能在控制Covid-19-19大流行的具有挑战性和严重的问题中具有真正的应用。
The SEIR model is a compartmental model used to simulate the dynamics of an epidemic. In this chapter, we introduce two control functions in the compartmental SEIR model representing vaccination and plasma transfusion. Optimal control problems are proposed to study the effects of these two control measures, on the reduction of infected individuals and increase of recovered ones, with minimal costs. Up to our knowledge, the plasma transfusion treatment has never been considered as a control strategy for epidemics mitigation. The proposed vaccination and treatment strategies may have a real application in the challenging and hard problem of controlling the COVID-19 pandemic.
