论文标题
噪声诱导的单分子驱动蛋白1的加速度
Noise-induced acceleration of single molecule kinesin-1
论文作者
论文摘要
在应用模仿细胞内活性波动的嘈杂的外部力时，观察到单驱素分子的运动。我们发现噪声下的动力素会加速，尤其是在增加大大阻碍负载时。该行为定量地符合一种描述具有简单两态反应的动力素运动的理论模型。动力学理论的普遍性表明，细胞内酶具有相似的噪声引起的加速度机制，即细胞中的主动波动不仅是噪声，而且被用来促进各种生理过程。
The movement of single kinesin molecules was observed while applying noisy external forces that mimic intracellular active fluctuations. We found kinesin accelerates under noise, especially when a large hindering load is added. The behavior quantitatively conformed to a theoretical model that describes the kinesin movement with simple two-state reactions. The universality of the kinetic theory suggests that intracellular enzymes share a similar noise-induced acceleration mechanism, i.e. active fluctuations in cells are not just noise but are utilized to promote various physiological processes.
