论文标题
用于发现哪些基因在神经炎症中差异表达的荟萃分析
Meta-analysis for Discovering Which Genes are Differentially Expressed in Neuroinflammation
论文作者
论文摘要
神经炎症是许多智人神经疾病的重要方面，在此过程中差异表达的基因应得到充分理解，以收集此类疾病的本质。我们已经对6个多物种（Homo Sapiens，Mus Musculus）数据集进行了一项荟萃分析（基于调整后的P值和LOGFC方案）（可在GEO上可用，用于基因表达综合的缩写），可通过微阵列技术获得。我们的分析表明，编码PLECKSTRIN同源性结构域和Galectin-9蛋白的基因参与小胶质细胞的神经炎症。
Neuroinflammation is a significant aspect of many neurological diseases of Homo sapiens, and the genes that are differentially expressed in this process should be well understood to gather the nature of such diseases. We have conducted a meta-analysis (based on a combined adjusted P value and logFC scheme) of 6 multi-species (Homo sapiens, Mus musculus) datasets (available on GEO, short for Gene Expression Omnibus) obtained through microarray technology. Our analysis shows that the genes coding pleckstrin homology domain and galectin-9 proteins take part in neuroinflammation in microglia.
