论文标题
用石墨烯纳米涂片的合成hachimoji DNA测序
Synthetic Hachimoji DNA Sequencing with Graphene Nanodevice
论文作者
论文摘要
基于密度合并的功能理论和非平衡绿色功能量子传输研究，我们证明了量子干扰对氧气终止的曲线赛的曲折石墨烯纳米亚素纳米电极之间放置的hachimoji合成核酸的横向电导的影响。我们认为，Qi效应可以很好地保存在核碱基分子和基于碳的纳米电极之间的PI-PI耦合中。我们的研究表明，根据核碱构象会影响横向电导变化的抗谐振或FANO共声等Qi效应。此外，在所有核碱基的旋转后，在电导率中观察到多达2-5个数量级的变化。电流 - 电压特性结果表明，对于所有五个核碱基，具有施加偏置电压的所有五个核碱基的电子隧穿电流都有明显的变化。不同的旋转角度在横向电导和隧穿电流特征中保持核碱基的独特特征。这两种功能都可以在精确的合成DNA测序设备中使用。
Based on combined density functional theory and nonequilibrium Greens function quantum transport studies, we have demonstrated quantum interference effects on the transverse conductance of Hachimoji synthetic nucleic acids placed between the oxygen-terminated zigzag graphene nanoribbon nanoelectrodes. We theorize that the QI effect could be well preserved in pi-pi coupling between a nucleobase molecule and the carbon-based nanoelectrode. Our study indicates that QI effects such as anti-resonance or Fano-resonance that affect the variation of transverse conductance depending on the nucleobase conformation. Further, a variation of up to 2-5 orders of magnitude is observed in the conductance upon rotation for all the nucleobases. The current-voltage characteristics results suggest a distinct variation in the electronic tunnelling current across the proposed nanogap device for all the five nucleobases with the applied bias voltage. The different rotation angles keep the distinct feature of the nucleobases in both transverse conductance and tunnelling current features. Both features could be utilized in an accurate synthetic DNA sequencing device.
