论文标题
使用主动物质将空间异质性引入易感性感染的流行病模型
Using Active Matter to Introduce Spatial Heterogeneity to the Susceptible-Infected-Recovered Model of Epidemic Spreading
论文作者
论文摘要
广泛使用的易感感染的（S-I-R）流行模型假定统一，混合良好的人群，空间异质性的融合仍然是一个主要挑战。了解混合假设的失败对于设计有效的疾病缓解方法很重要。我们将运行和摔倒的自行量活跃物质系统与S-I-R模型结合在一起，以捕获空间疾病的影响。在运动性诱导的相位分离状态下，无论是有或没有猝灭障碍的过程，我们都发现了两个流行病制。对于低传播性，淬火障碍降低了流行病的频率并增加了平均持续时间。为了高可传播性，流行病作为正面蔓延，流行曲线对淬火障碍不太敏感。但是，在这种制度内，淬火障碍有可能通过创建较高颗粒密度的区域来增强触觉。我们讨论如何使用带有移动光学陷阱的人工游泳者在反馈循环中操作的系统。
The widely used susceptible-infected-recovered (S-I-R) epidemic model assumes a uniform, well-mixed population, and incorporation of spatial heterogeneities remains a major challenge. Understanding failures of the mixing assumption is important for designing effective disease mitigation approaches. We combine a run-and-tumble self-propelled active matter system with an S-I-R model to capture the effects of spatial disorder. Working in the motility-induced phase separation regime both with and without quenched disorder, we find two epidemic regimes. For low transmissibility, quenched disorder lowers the frequency of epidemics and increases their average duration. For high transmissibility, the epidemic spreads as a front and the epidemic curves are less sensitive to quenched disorder; however, within this regime it is possible for quenched disorder to enhance the contagion by creating regions of higher particle densities. We discuss how this system could be realized using artificial swimmers with mobile optical traps operated on a feedback loop.
