论文标题
压力诱导的螺旋细菌的形状转移
Pressure-induced Shape-shifting of Helical Bacteria
论文作者
论文摘要
许多细菌物种的形式都是螺旋的，包括幽门螺杆菌的广泛病原体。最近对幽门螺杆菌的实验的动机，表明细胞壁合成不是均匀的，我们研究了由弹性异质性诱导的螺旋细胞形状的可能形成。我们在实验和理论上表明，可以通过用螺旋增强线加压弹性圆柱形血管来产生螺旋形态发生。加压螺旋的性质高度取决于增强区域的初始螺旋角。我们发现陡峭的角度导致弯曲的螺旋，令人惊讶的是，加压后端到端距离降低。这项工作有助于解释产生螺旋细胞形态的可能机制，并可能激发新型压力控制的螺旋致动器的设计。
Many bacterial species are helical in form, including the widespread pathogen H. pylori. Motivated by recent experiments on H. pylori showing that cell wall synthesis is not uniform, we investigate the possible formation of helical cell shape induced by elastic heterogeneity. We show, experimentally and theoretically, that helical morphogenesis can be produced by pressurizing an elastic cylindrical vessel with helical reinforced lines. The properties of the pressurized helix are highly dependent on the initial helical angle of the reinforced region. We find that steep angles result in crooked helices with, surprisingly, reduced end-to-end distance upon pressurization. This work helps to explain the possible mechanisms for the generation of helical cell morphologies and may inspire the design of novel pressure-controlled helical actuators.
