论文标题
介电调节双门双层电极有机薄膜基于晶体管的生物传感器无标记检测：仿真研究和灵敏度分析
Dielectric-Modulated Double Gate Bilayer Electrode Organic Thin Film Transistor-based Biosensor for Label-Free Detection: Simulation Study and Sensitivity Analysis
论文作者
论文摘要
介电调节的双门双层电极有机薄膜晶体管（DMDGBE-OTFT）的传感器建议用于无标记的无标签生物分子检测。 DMDGBE-OTFT的双门用于在有机半导体的两侧创建两个对称门底板区域。生物分子在两个门底板区域中的平行固定固定改变了DMDGBEOTFT的流动（ION）。双层电极还用于显着降低屏障高度，以增强所提出的设备的性能。排水电流的变化已被用来评估DMDGBE-OTFT对具有不同介电常数和相应电荷密度的生物分子识别的敏感性，而当生物分子固定在栅极底层底片中时，使用基于2D物理学的数值模拟。 Atlas TCAD工具用于研究DMDGBE-OTFT的灵敏度性能。与最近报道的基于OTFT的生物传感器相比，提出的DMDGBE-OTFT具有24.2％的敏感性，用于无标记的生物分子检测。 DMDGBE-OTFT生物传感器将来具有很大的柔性生物传感应用，因为其灵活性，高灵敏度，生物相容性和低成本。
A dielectric-modulated double gate bilayer electrodes organic thin-film transistor (DMDGBE-OTFT) based sensor is proposed for label-free biomolecule detection. The double gate of DMDGBE-OTFT is used for creating two symmetrical gates underlap regions on both sides of the organic semiconductor. The parallel immobilization of biomolecule in two gates underlaps region changes the on-current (ION) of the DMDGBEOTFT. Bilayer electrode is also used for significant reduction of barrier height to enhance the performance of the proposed device. The change in the drain current has been utilized to evaluate the sensitivity of the DMDGBE-OTFT for biomolecule recognition having different dielectric constants and corresponding charge densities using 2-D physics-based numerical simulation when biomolecules are immobilized in the gate underlap area. The ATLAS TCAD tool is used to investigate the sensitivity performance of the DMDGBE-OTFT. The proposed DMDGBE-OTFT has 24.2% higher sensitivity in comparison to the recently reported OTFT-based biosensors for label-free detection of biomolecules. The DMDGBE-OTFT biosensor has a lot of potential for flexible biosensing applications in the future because of its flexibility, high sensitivity, biocompatibility and low cost.
