论文标题
通过各种快速抗原试验
A Comparison Study of the Detection Limit of Omicron SARS-CoV-2 Nucleocapsid by various Rapid Antigen Tests
论文作者
论文摘要
自2019年12月在武汉的第一个Covid-19疾病病例以来，全球努力努力减少急性呼吸综合症冠状病毒SARS-COV-2的传播。全世界许多国家都决定实施当地的锁定，以减少人与人之间的互动，面具成为强制性的，尤其是在封闭的空间中，并且对社会距离有一般要求。但是，减少人群中感染持续传播的最有效方法，与此同时，请尽早发现感染传染性的人。到目前为止，SARS-COV-2检测最可靠的方法是反向转录酶PCR检验（RT-PCR）。即使样品中只有一个RNA链，也可以检测到病毒，并同时运行数百个样品。该方法有一些缺点，例如高成本，很耗时，需要医疗实验室和熟练的员工执行测试的需求，以及主要缺陷：缺乏适当数量的可用测试。后来突出的Omicron变体（B.1.1.529）及其衍生物由于其可传播性增强而导致受感染者的数量大大增加。这一切都强调了对易于使用，廉价和可用检测测试的高需求。
Since the first case of COVID-19 disease in Wuhan in December 2019, there is a worldwide struggle to reduce the transmission of acute respiratory syndrome coronavirus SARS-CoV-2. Many countries worldwide decided to impose local lockdowns in order to reduce person-to-person interactions, masks became obligatory especially in closed spaces, and there was a general requirement for social distance. However, the most efficient method to reduce continuing spreading of infection among the population, and in the meantime maintain a regular daily life, is early detection of infected contagious people. Up to now, the most reliable method for SARS-CoV-2 detection is reverse-transcriptase PCR test (RT-PCR). It is possible to detect the virus even if there is only one RNA strand in the sample, and run hundreds of samples simultaneously. This method has a few disadvantages, such as high cost, is time consuming, the need for medical laboratories and skilled staff to perform the test, and the major flaw: the lack of appropriate number of available tests. The latterly prominent Omicron variant (B.1.1.529) and its derivatives have caused a tremendous increase in the number of infected people due to its enhanced transmissibility. This all emphasizes the high demand for easy-to-use, cheap and available detection tests.
