论文标题

动态绝对浓度鲁棒性的功率发动机负载形式

Power-engine-load form for dynamic absolute concentration robustness

论文作者

Joshi, Badal, Craciun, Gheorghe

论文摘要

在反应网络中,具有动态绝对浓度鲁棒性(动态ACR)特性的物种的浓度会收敛到相同的值,而与整体初始值无关。该属性赋予生化网络具有鲁棒性,因此对于在高度可变的环境中运行至关重要。重要的是要确定动态系统的结构以及动态ACR所需的约束。我们提出了动态ACR的功率发动机载荷形式,并根据此形式获得有关与ACR值收敛的结果。

In a reaction network, the concentration of a species with the property of dynamic absolute concentration robustness (dynamic ACR) converges to the same value independent of the overall initial values. This property endows a biochemical network with output robustness and therefore is essential for its functioning in a highly variable environment. It is important to identify structure of the dynamical system as well as constraints required for dynamic ACR. We propose a power-engine-load form of dynamic ACR and obtain results regarding convergence to the ACR value based on this form.

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