论文标题
用于骨科应用的新型MG-SN-GE三元合金的体外评估
In vitro evaluation of a novel Mg-Sn-Ge ternary alloy for orthopedic applications
论文作者
论文摘要
镁（MG）及其合金因其出色的可生物降解特性和生物相容性而引起了极大的关注。新型的MG-SN-GE三元MG合金是作为骨科应用的潜在可生物降解材料而开发的，因为它们的合金元素自然存在于人类中。这些合金的可行性是根据机械性能，降解，细胞相容性和血流相容性的。通过增加GE含量，MG-2SN-XGE合金的硬度和弹性模量得到了显着改善。在所有合金中，MG-2SN-3GE合金显示出出色的生物降解特性，如电化学测试和氢进化所证明的那样。在腐蚀的合金表面上检测到的降解产物在较高的GE水平下弱化。体外细胞毒性测定法和溶血试验表明，除MG-2SN-2GE合金外，MG-2SN-XGE合金表现出有利的生物相容性和血流相容性。
Magnesium (Mg) and its alloys have attracted considerable attention owing to their excellent biodegradable properties and biocompatibility. Novel Mg-Sn-Ge ternary Mg alloys were developed as potential biodegradable materials for orthopedic applications because of their alloying elements naturally present in humans. The feasibility of these alloys was investigated in terms of mechanical properties, degradation, cytocompatibility, and hemocompatibility. The hardness and elastic modulus of Mg-2Sn-xGe alloys were improved significantly by increasing the Ge content. Among all the alloys, the Mg-2Sn-3Ge alloy displays outstanding biodegradable properties, as evidenced by the electrochemical tests and hydrogen evolution. The degradation products detected on the corroded alloy surfaces weaken at higher Ge levels. The in vitro cytotoxicity assay and hemolysis test showed that the Mg-2Sn-xGe alloys exhibit favorable biocompatibility and hemocompatibility, except for the Mg-2Sn-2Ge alloy.
